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Western blot analysis of BiP/GRP78 (Cterminus) in Hela, C6, Lncap and MDA-MB-468 lysates using BiP/GRP78 (Cterminus) antibody.

Immunocytochemistry analysis of GRP78 BiP in HeLa using BiP/GRP78 (Cterminus) antibody.

Immunohistochemistry analysis of paraffin-embedded Colorectal cancer using BiP/GRP78 (Cterminus) antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Mouse Monoclonal Antibody to GRP78 BiP

货号：
P20709
别名：
HSPA5; GRP78; 78 kDa glucose-regulated protein; GRP-78; Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78; Heat shock 70 kDa protein 5; Immunoglobulin heavy chain-binding protein; BiP
产品上架时间：
2024-01-01
应用：
WB,IHC,IF
反应种属：
Human,Rat
抗体类型：
Primary antibody
Swissprot：
P11021
规格：

100μl
50μl
20μl
数量：

-

+
说明书：

目录价¥2180

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Mouse Monoclonal Antibody to GRP78 BiP

Description
When Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) (PubMed 8020977) pointed out that one of these, GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER).

Description

When Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) (PubMed 8020977) pointed out that one of these, GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER).

Specification
Aliases	HSPA5; GRP78; 78 kDa glucose-regulated protein; GRP-78; Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78; Heat shock 70 kDa protein 5; Immunoglobulin heavy chain-binding protein; BiP
Entrez GeneID	3309
Swissprot	P11021
clone	7B5
WB Predicted band size	Calculated MW: 72 kDa; Observed MW: 78 kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Rat
Immunogen	Purified recombinant human BiP/GRP78 (C-terminus) protein fragments expressed in E.coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.