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Mouse Monoclonal Antibody to GITR
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货号:
31522 -
别名:
TNFRSF18; AITR; CD357; GITR-D -
产品上架时间:
2024-01-01 -
应用:
FCM -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
Q9Y5U5 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180
Mouse Monoclonal Antibody to GITR
Description |
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This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
References |
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1.PLoS One. 2015 May 14;10(5):e0127334. 2.Clin Dev Immunol. 2013;2013:340751. |
Specification |
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Aliases | TNFRSF18; AITR; CD357; GITR-D |
Entrez GeneID | 8784 |
Swissprot | Q9Y5U5 |
clone | 6H8B9 |
WB Predicted band size | 26kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human GITR (AA: 184-241) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
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FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#31522
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