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Immunohistochemistry analysis of paraffin-embedded Human Lung Carcinoma Tissue using JAK2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunohistochemical analysis of paraffin-embedded Human tonsils using JAK2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Mouse Monoclonal Antibody to JAK2

货号：
P20502
别名：
JAK2; Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2
产品上架时间：
2024-01-01
应用：
IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
O60674
规格：

100μl
50μl
20μl
数量：

-

+
说明书：

目录价¥2180

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Mouse Monoclonal Antibody to JAK2

Description
Phosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription. For example, cell stimulation with erythropoietin (EPO) during erythropoiesis leads to JAK2 autophosphorylation, activation, and its association with erythropoietin receptor (EPOR) that becomes phosphorylated in its cytoplasmic domain. Then, STAT5 (STAT5A or STAT5B) is recruited, phosphorylated and activated by JAK2.

Description

Phosphorylated STATs then form homodimer or heterodimers and translocate to the nucleus to activate gene transcription. For example, cell stimulation with erythropoietin (EPO) during erythropoiesis leads to JAK2 autophosphorylation, activation, and its association with erythropoietin receptor (EPOR) that becomes phosphorylated in its cytoplasmic domain. Then, STAT5 (STAT5A or STAT5B) is recruited, phosphorylated and activated by JAK2.

Specification
Aliases	JAK2; Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2
Entrez GeneID	3717
Swissprot	O60674
clone	10A4
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthetic peptide conjugated to KLH.
Formulation	Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.