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Western blot analysis of Phospho-HDAC5 (Ser498) in 293 lysates using Phospho-HDAC5 (Ser498) antibody.

Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue using HDAC5(Phospho-Ser498) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right.

Rabbit Polyclonal Antibody to Phospho-HDAC5 (Ser498)

货号：
P20308
别名：
HD5; NY-CO-9
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human,Mouse
抗体类型：
Primary antibody
Swissprot：
Q9UQL6
规格：

100μl
50μl
20μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Polyclonal Antibody to Phospho-HDAC5 (Ser498)

Description
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.

Description

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.

Specification
Aliases	HD5; NY-CO-9
Entrez GeneID	10014
Swissprot	Q9UQL6
WB Predicted band size	Calculated MW: 122 kDa; Observed MW: 122 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Synthetic peptide of human HDAC5
Formulation	Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.