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Western blot analysis of Phospho-ErbB 2 (Tyr1221/Tyr1222) in various lysates using Phospho-ErbB 2 (Tyr1221/Tyr1222) antibody.

Western blot analysis of Phospho-ErbB 2 (Tyr1221/Tyr1222) in SKOV-3 lysates treated with EGF, using HER2 (Phospho-Tyr1221/Tyr122, 2) antibody. The lane on the right is blocked with the Phospho- peptide.

Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma, using HER2 (Phospho-Tyr1221/Tyr122, 2) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right.

Rabbit Polyclonal Antibody to Phospho-ErbB 2 (Tyr1221/Tyr1222)

货号：
P20286
别名：
ERBB2; HER2; MLN19; NEU; NGL; Receptor tyrosine-protein kinase erbB-2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; CD antigen CD340
产品上架时间：
2024-01-01
应用：
WB,IP,IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
P04626
规格：

100μl
50μl
20μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to Phospho-ErbB 2 (Tyr1221/Tyr1222)

Description
This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase.

Description

This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase.

Specification
Aliases	ERBB2; HER2; MLN19; NEU; NGL; Receptor tyrosine-protein kinase erbB-2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; CD antigen CD340
Entrez GeneID	2064
Swissprot	P04626
WB Predicted band size	Calculated MW: 138 kDa; Observed MW: 180 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	The antiserum was produced against synthesized peptide derived from human HER2 around the phosphorylation site of Tyr1221/Tyr1222. AA range:1191-1240
Formulation	Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.