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Western blot analysis of Phospho-TAOK1(Ser181)/TAOK2 (Ser181)/TAOK3 (Ser177) in 3T3 lysates using Phospho-TAOK1/2/3 (Ser181/Ser181/Ser177) antibody.

Western blot analysis of TAOK1 (Phospho-Ser181)/TAOK2 (Phospho-Ser181)/TAOK3 (Phospho-Ser177) in Hela, A549, HL-60, U2OS, C6 lysates using TAOK1 (Phospho-Ser181)/TAOK2 (Phospho-Ser181)/TAOK3 (Phospho-Ser177) antibody.

Immunohistochemistry analysis of paraffin-embedded Human tonsil using TAOK1 (Phospho-Ser181)/TAOK2 (Phospho-Ser181)/TAOK3 (Phospho-Ser177) antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Rabbit Monoclonal Antibody to Phospho-TAOK1/2/3 (Ser181/Ser181/Ser177)

货号：
P20206
别名：
DPK; JIK; hKFC-A; MAP3K18
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human,Mouse,Rat
抗体类型：
Primary antibody
Swissprot：
Q7L7X3/Q9H2K8/Q9UL54
规格：

100μl
50μl
20μl
数量：

-

+
说明书：

目录价¥2180

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Rabbit Monoclonal Antibody to Phospho-TAOK1/2/3 (Ser181/Ser181/Ser177)

Description
Serine/threonine-protein kinase involved in various processes such as p38/MAPK14 stress-activated MAPK cascade, DNA damage response and regulation of cytoskeleton stability. Phosphorylates MAP2K3, MAP2K6 and MARK2. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade by mediating phosphorylation and subsequent activation of the upstream MAP2K3 and MAP2K6 kinases. Involved in G-protein coupled receptor signaling to p38/MAPK14. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of MAP2K3 and MAP2K6.

Description

Serine/threonine-protein kinase involved in various processes such as p38/MAPK14 stress-activated MAPK cascade, DNA damage response and regulation of cytoskeleton stability. Phosphorylates MAP2K3, MAP2K6 and MARK2. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade by mediating phosphorylation and subsequent activation of the upstream MAP2K3 and MAP2K6 kinases. Involved in G-protein coupled receptor signaling to p38/MAPK14. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of MAP2K3 and MAP2K6.

Specification
Aliases	DPK; JIK; hKFC-A; MAP3K18
Entrez GeneID	51347/57551/9344
Swissprot	Q7L7X3/Q9H2K8/Q9UL54
WB Predicted band size	Calculated MW: 116 kDa; Observed MW: 105,116,138 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	A synthetic phosphopeptide corresponding to residues surrounding Ser181 of human TAOK1
Formulation	Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.