Rabbit Monoclonal Antibody to Phospho-Dishevelled 2 (Ser143)

Description
Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Participates both in canonical and non-canonical Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling.

Specification
Aliases	DSH homolog 2
Entrez GeneID	1856
Swissprot	O14641
WB Predicted band size	Calculated MW: 79 kDa; Observed MW: 90-95 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	A synthetic phosphopeptide corresponding to residues surrounding Ser143 of human Dishevelled 2
Formulation	Purified antibody in TBS with 0.05% sodium azide,0.05%BSA and 50% glycerol.

Application
WB	1/500-1/1000