提醒成功
搜索
Mouse Monoclonal Antibody to LILRB2
-
货号:
31475 -
别名:
ILT4; LIR2; CD85D; ILT-4; LIR-2; MIR10; MIR-10 -
产品上架时间:
2024-01-01 -
应用:
WB,FCM -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
Q8N423 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180
Mouse Monoclonal Antibody to LILRB2
Description |
---|
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. |
References |
---|
1.J Immunol Res. 2016;2016:4163094.2.PLoS One. 2014 Mar 27;9(3):e92018. |
Specification |
|
---|---|
Aliases | ILT4; LIR2; CD85D; ILT-4; LIR-2; MIR10; MIR-10 |
Entrez GeneID | 10288 |
Swissprot | Q8N423 |
clone | 2G7E11 |
WB Predicted band size | 65kDa |
Host/Isotype | Mouse IgG2a |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human LILRB2 (AA: 51-184) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
---|---|
WB | 1/500 - 1/2000 |
FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
- Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
- Western blot analysis using LILRB2 mouse mAb against MOLT4 (1) and K562 (2) cell lysate.
- Flow cytometric analysis of HL-60 cells using LILRB2 mouse mAb (green) and negative control (red).
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#31475
相关产品