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Western blot analysis of Cleaved-Caspase 6 p18 in various lysates using Cleaved-Caspase 6 p18 antibody.
Western blot analysis of Cleaved-Caspase 6 p18 in 293 lysates using Cleaved-Caspase6 p18 (D179) antibody.
Western blot analysis of Cleaved-Caspase 6 p18 in 293 lysates treated with Etoposide using Cleaved-Caspase 6 p18 antibody.The lane on the right is blocked with the synthesized peptide.
Immunohistochemistry analysis of paraffin-embedded Human lung carcinoma tissue using Caspase 6 (Cleaved-Asp16, 2) antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right.

Rabbit Polyclonal Antibody to Cleaved-Caspase 6 p18

  • 货号:

    P20029
  • 别名:

    CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC
  • 反应种属:

    Human,Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P55212
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Polyclonal Antibody to Cleaved-Caspase 6 p18

Description

Caspase-6 (Mch2) is one of the major executioner caspases functioning in cellular apoptotic processes. Upon apoptotic stimulation, initiator caspases such as caspase-9 are cleaved and activated. The activated upstream caspases further process downstream executioner caspases, such as caspase-3 and caspase-6, by cleaving them into large and small subunits, thereby initiating a caspase cascade leading to apoptosis. One of the major targets for caspase-6 is the membrane associated protein lamin A.

Specification

Aliases CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2
Entrez GeneID 839
Swissprot P55212
WB Predicted band size Calculated MW: 33 kDa; Observed MW: 20,35 kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Rat
Immunogen The antiserum was produced against synthesized peptide derived from human Caspase 6. AA range:130-179
Formulation Purified antibody in PBS with 0.05% sodium azide,0.5%BSA and 50% glycerol.

Application

WB 1/500-1/1000
IHC 1/50-1/100
ELISA 1/10000