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Mouse Monoclonal Antibody to CD49B
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货号:
31439 -
别名:
ITGA2; BR; GPIa; HPA-5; VLA-2; VLAA2 -
产品上架时间:
2024-01-01 -
应用:
ICC,FCM -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
P17301 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180
Mouse Monoclonal Antibody to CD49B
Description |
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This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants. |
References |
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1.Arch Oral Biol. 2014 Mar;59(3):283-8. 2.Int J Clin Exp Pathol. 2013 Apr 15;6(5):841-52. |
Specification |
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Aliases | ITGA2; BR; GPIa; HPA-5; VLA-2; VLAA2 |
Entrez GeneID | 3673 |
Swissprot | P17301 |
clone | 5E3A8 |
WB Predicted band size | 129.3kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human CD49B (AA: extra 994-1132) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
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ICC | 1/100 - 1/500 |
FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
- Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
- Immunofluorescence analysis of Hela cells using CD49B mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
- Flow cytometric analysis of HT1080 cells using CD49B mouse mAb (green) and negative control (red).
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#31439
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