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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Immunofluorescence analysis of Hela cells using CD49B mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
Flow cytometric analysis of HT1080 cells using CD49B mouse mAb (green) and negative control (red).

Mouse Monoclonal Antibody to CD49B

  • 货号:

    31439
  • 别名:

    ITGA2; BR; GPIa; HPA-5; VLA-2; VLAA2
  • 产品上架时间:

    2024-01-01
  • 应用:

    ICC,FCM
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P17301
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

加入购物车

Mouse Monoclonal Antibody to CD49B

Description

This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.

References

1.Arch Oral Biol. 2014 Mar;59(3):283-8.
2.Int J Clin Exp Pathol. 2013 Apr 15;6(5):841-52.

Specification

Aliases ITGA2; BR; GPIa; HPA-5; VLA-2; VLAA2
Entrez GeneID 3673
Swissprot P17301
clone 5E3A8
WB Predicted band size 129.3kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human CD49B (AA: extra 994-1132) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

ICC 1/100 - 1/500
FCM 1/200 - 1/400
ELISA 1/10000