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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western blot analysis using CD268 mouse mAb against C6 (1) cell lysate.
Flow cytometric analysis of Raji cells using CD268 mouse mAb (green) and negative control (red).

Mouse Monoclonal Antibody to CD268

  • 货号:

    31414
  • 别名:

    TNFRSF13C; BAFFR; CVID4; BAFF-R; BROMIX; prolixin
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,FCM
  • 反应种属:

    Human,Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q96RJ3
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

加入购物车

Mouse Monoclonal Antibody to CD268

Description

B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.

References

1.Mol Cancer Ther. 2014 Jun;13(6):1567-77.
2.Mol Cell Biochem. 2011 Nov;357(1-2):21-30.

Specification

Aliases TNFRSF13C; BAFFR; CVID4; BAFF-R; BROMIX; prolixin
Entrez GeneID 115650
Swissprot Q96RJ3
clone 5A9B6
WB Predicted band size 18.9kDa
Host/Isotype Mouse IgG2b
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Rat
Immunogen Purified recombinant fragment of human CD268 (AA: extra 1-78) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

WB 1/500 - 1/2000
FCM 1/200 - 1/400
ELISA 1/10000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#31414