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Mouse Monoclonal Antibody to CD268
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货号:
31414 -
别名:
TNFRSF13C; BAFFR; CVID4; BAFF-R; BROMIX; prolixin -
产品上架时间:
2024-01-01 -
应用:
WB,FCM -
反应种属:
Human,Rat -
抗体类型:
Primary antibody -
Swissprot:
Q96RJ3 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180
Mouse Monoclonal Antibody to CD268
Description |
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B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. |
References |
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1.Mol Cancer Ther. 2014 Jun;13(6):1567-77. 2.Mol Cell Biochem. 2011 Nov;357(1-2):21-30. |
Specification |
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Aliases | TNFRSF13C; BAFFR; CVID4; BAFF-R; BROMIX; prolixin |
Entrez GeneID | 115650 |
Swissprot | Q96RJ3 |
clone | 5A9B6 |
WB Predicted band size | 18.9kDa |
Host/Isotype | Mouse IgG2b |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Rat |
Immunogen | Purified recombinant fragment of human CD268 (AA: extra 1-78) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
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WB | 1/500 - 1/2000 |
FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#31414
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