提醒成功
搜索
Mouse Monoclonal Antibody to OX40
-
货号:
31366 -
别名:
TNFRSF4; ACT35; CD134; IMD16; TXGP1L -
应用:
FCM -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
P43489 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180
Mouse Monoclonal Antibody to OX40
Description |
---|
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. |
References |
---|
1.Oncotarget. 2015 Nov 10;6(35):37588-99. 2.Hepatology. 2014 Nov;60(5):1494-507. |
Specification |
|
---|---|
Aliases | TNFRSF4; ACT35; CD134; IMD16; TXGP1L |
Entrez GeneID | 7293 |
Swissprot | P43489 |
clone | 2D1B8 |
WB Predicted band size | 29.3kDa |
Host/Isotype | Mouse IgG2b |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human OX40 (AA: extra 29-214) expressed in HEK293 cells. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
---|---|
FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#31366
相关产品