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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western blot analysis using Dynamin-2 mouse mAb against Hela (1), U251 (2), K562 (3), Jurkat (4), and Ramos (5) cell lysate.
Flow cytometric analysis of Hela cells using *** mouse mAb (green) and negative control (red).

Mouse Monoclonal Antibody to Dynamin-2

  • 货号:

    31335
  • 别名:

    DNM2;DYN2; CMT2M; DYNII; LCCS5; CMTDI1; CMTDIB; DI-CMTB
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,FCM
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P50570 
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to Dynamin-2

Description

Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined.

References

1.Cancer Med. 2014 Feb;3(1):14-24.
2.Eur J Obstet Gynecol Reprod Biol. 2012 Oct;164(2):180-4.

Specification

Aliases DNM2;DYN2; CMT2M; DYNII; LCCS5; CMTDI1; CMTDIB; DI-CMTB
Entrez GeneID 1785
Swissprot P50570 
clone 3F5F3
WB Predicted band size 98kDa
Host/Isotype Mouse IgG2a
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human Dynamin-2 (AA: 520-744) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

WB 1/250 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000