请登录
搜索 英文站
栏目

提醒成功

请输入手机号/邮箱号
请输入密码

账号密码登录

微信/QQ登录 微信/QQ登录

没有账号? 立即注册

搜索
Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western blot analysis using CD195 mouse mAb against MOLT4 (1), L-02 (2), SPA-C-1 (3), A549 (4), and C6 (5) cell lysate.
Flow cytometric analysis of K562 cells using CD195 mouse mAb (green) and negative control (red).
Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using CD195 mouse mAb with DAB staining.
Immunohistochemical analysis of paraffin-embedded human bladder cancer tissues using CD195 mouse mAb with DAB staining.

Mouse Monoclonal Antibody to CD195

  • 货号:

    31326
  • 别名:

    CCR5; CKR5; CCR-5; CKR-5; CCCKR5; CMKBR5; IDDM22; CC-CKR-5
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC,FCM
  • 反应种属:

    Human,Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P51681
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

加入购物车

Mouse Monoclonal Antibody to CD195

Description

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. An allelic polymorphism in this gene results in both functional and non-functional alleles; the reference genome represents the functional allele. Two transcript variants encoding the same protein have been found for this gene.

References

1.J Leukoc Biol. 2015 Jul;98(1):59-71.
2.J Gen Virol. 2015 Aug;96(8):2074-8.

Specification

Aliases CCR5; CKR5; CCR-5; CKR-5; CCCKR5; CMKBR5; IDDM22; CC-CKR-5
Entrez GeneID 1234
Swissprot P51681
clone 6G11D1
WB Predicted band size 40.5kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Rat
Immunogen Purified recombinant fragment of human CD195 (AA: extra mix) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

WB 1/500 - 1/2000
IHC 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000