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Mouse Monoclonal Antibody to BAK1
-
货号:
31274 -
别名:
BAK; CDN1; BCL2L7; BAK-LIKE -
产品上架时间:
2024-01-01 -
应用:
IHC,FCM -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
Q16611 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180
Mouse Monoclonal Antibody to BAK1
Description |
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The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. |
References |
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1.Cell Death Differ. 2015 Oct;22(10):1665-75. 2.PLoS Pathog. 2013;9(10):e1003658. |
Specification |
|
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Aliases | BAK; CDN1; BCL2L7; BAK-LIKE |
Entrez GeneID | 578 |
Swissprot | Q16611 |
clone | 2H9H7 |
WB Predicted band size | 23.4kDa |
Host/Isotype | Mouse IgG2b |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human BAK1 (AA: 29-187) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
---|---|
IHC | 1/200 - 1/1000 |
FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
- Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
- Flow cytometric analysis of Hela cells using BAK1 mouse mAb (green) and negative control (red).
- Immunohistochemical analysis of paraffin-embedded human bladder cancer tissues using BAK1 mouse mAb with DAB staining.
- Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using BAK1 mouse mAb with DAB staining.
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#31274
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