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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Western blot analysis using AP2M1 mouse mAb against COS7 (1), SK-Br-3 (2), MCF-7 (3), T47D (4), and HEK293 (5) cell lysate.

Mouse Monoclonal Antibody to AP2M1

  • 货号:

    31243
  • 别名:

    mu2; AP50; CLAPM1
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB
  • 反应种属:

    Human,Monkey
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q96CW1
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to AP2M1

Description

This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Three transcript variants encoding different isoforms have been found for this gene.

References

1.PLoS Pathog. 2012;8(8):e1002845.
2.Proc Natl Acad Sci U S A. 2007 Feb 20;104(8):2991-6.

Specification

Aliases mu2; AP50; CLAPM1
Entrez GeneID 1173
Swissprot Q96CW1
clone 4F1B2
WB Predicted band size 49.7kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Monkey
Immunogen Purified recombinant fragment of human AP2M1 (AA: 298-435) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

WB 1/300 - 1/800
ELISA 1/10000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#31243