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Mouse Monoclonal Antibody to RUNX3
Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Mouse Monoclonal Antibody to RUNX3
Immunofluorescence analysis of Hela cells using RUNX3 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
Mouse Monoclonal Antibody to RUNX3
Flow cytometric analysis of Hela cells using RUNX3 mouse mAb (green) and negative control (red).
Mouse Monoclonal Antibody to RUNX3
Immunohistochemical analysis of paraffin-embedded human esophageal cancer tissues using RUNX3 mouse mAb with DAB staining.
Mouse Monoclonal Antibody to RUNX3
Immunohistochemical analysis of paraffin-embedded human stomach cancer tissues using RUNX3 mouse mAb with DAB staining.
Mouse Monoclonal Antibody to RUNX3
Mouse Monoclonal Antibody to RUNX3
Mouse Monoclonal Antibody to RUNX3
Mouse Monoclonal Antibody to RUNX3
Mouse Monoclonal Antibody to RUNX3

Mouse Monoclonal Antibody to RUNX3

  • 货号:

    31207
  • 别名:

    AML2; CBFA3; PEBP2aC
  • 产品上架时间:

    2024-01-01
  • 应用:

    IHC,IF,FCM
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q13761
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to RUNX3

Description

This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants.

References

1.Genet Mol Res. 2015 Dec 1;14(4):15505-10.
2.J Pathol. 2015 Dec;237(4):520-31.

Specification

Aliases AML2; CBFA3; PEBP2aC
Entrez GeneID 864
Swissprot Q13761
clone 7E2B8
WB Predicted band size 44.4kDa
Host/Isotype Mouse IgG2b
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human RUNX3 (AA: 294-429) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

IHC 1/200 - 1/1000
IF/ICC 1/50 - 1/250
FCM 1/200 - 1/400
ELISA 1/10000