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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Immunofluorescence analysis of Hela cells using SOD2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Flow cytometric analysis of Hela cells using SOD2 mouse mAb (green) and negative control (red).

Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissues using SOD2 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using SOD2 mouse mAb with DAB staining.

Mouse Monoclonal Antibody to SOD2

货号：
31094
别名：
IPOB; IPO-B; MNSOD; MVCD6; Mn-SOD
产品上架时间：
2024-01-01
应用：
IHC,IF,FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
P04179
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Mouse Monoclonal Antibody to SOD2

Description
This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1.

Description

This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 1.

References
1.Dis Markers. 2015;2015:746329. 2.Free Radic Biol Med. 2015 Dec;89:379-86.

Specification
Aliases	IPOB; IPO-B; MNSOD; MVCD6; Mn-SOD
Entrez GeneID	6648
Swissprot	P04179
clone	8H3D2
WB Predicted band size	24.7kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant fragment of human SOD2 (AA: 1-222) expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide