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Mouse Monoclonal Antibody to MITF
-
货号:
31088 -
别名:
MI; WS2; CMM8; WS2A; bHLHe32 -
产品上架时间:
2024-01-01 -
应用:
WB,FCM -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
O75030 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180
Mouse Monoclonal Antibody to MITF
Description |
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This gene encodes a transcription factor that contains both basic helix-loop-helix and leucine zipper structural features. It regulates the differentiation and development of melanocytes retinal pigment epithelium and is also responsible for pigment cell-specific transcription of the melanogenesis enzyme genes. Heterozygous mutations in the this gene cause auditory-pigmentary syndromes, such as Waardenburg syndrome type 2 and Tietz syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. |
References |
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1.Proc Natl Acad Sci U S A. 2015 Feb 3;112(5):E420-9. 2.Cell Mol Life Sci. 2015 Apr;72(7):1249-60. |
Specification |
|
---|---|
Aliases | MI; WS2; CMM8; WS2A; bHLHe32 |
Entrez GeneID | 4286 |
Swissprot | O75030 |
clone | 8F1G5 |
WB Predicted band size | 58.8kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human MITF (AA: 1-114) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
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WB | 1/500 - 1/2000 |
FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
- Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
- Western blot analysis using MITF mouse mAb against PANC-1 (1) and A549 (2) cell lysate.
- Flow cytometric analysis of Hela cells using MITF mouse mAb (green) and negative control (red).
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#31088
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