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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Immunofluorescence analysis of Hela cells using PTPN14 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Flow cytometric analysis of Hela cells using PTPN14 mouse mAb (green) and negative control (red).

Immunohistochemical analysis of paraffin-embedded human breast cancer tissues using PTPN14 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using PTPN14 mouse mAb with DAB staining.

Mouse Monoclonal Antibody to PTPN14

货号：
31048
别名：
PEZ; PTP36
产品上架时间：
2024-01-01
应用：
IHC,IF,FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q15678
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Mouse Monoclonal Antibody to PTPN14

Description
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. It appears to regulate lymphatic development in mammals, and a loss of function mutation has been found in a kindred with a lymphedema-choanal atresia.

Description

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. It appears to regulate lymphatic development in mammals, and a loss of function mutation has been found in a kindred with a lymphedema-choanal atresia.

References
1.Oncogene. 2013 Apr 18;32(16):2087-95. 2.PLoS One. 2013 Apr 16;8(4):e61916.

Specification
Aliases	PEZ; PTP36
Entrez GeneID	5784
Swissprot	Q15678
clone	2B3H7
WB Predicted band size	135.3kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant fragment of human PTPN14 (AA: 896-1169) expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide