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Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
Flow cytometric analysis of Hela cells using DNMT3A mouse mAb (green) and negative control (red).
Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using DNMT3A mouse mAb with DAB staining.
Mouse Monoclonal Antibody to DNMT3A
-
货号：
31016 -
别名：
TBRS; DNMT3A2; M.HsaIIIA -
应用：
IHC,FCM -
反应种属：
Human -
抗体类型：
Primary antibody -
Swissprot：
Q9Y6K1 -
规格：
-
数量：
-+ -
说明书：
目录价¥2180
Mouse Monoclonal Antibody to DNMT3A
Description |
|---|
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. |
References |
|---|
| 1.PLoS One. 2014 Jun 17;9(6):e93353. 2.Asian Pac J Cancer Prev. 2013;14(10):5713-8. |
Specification |
|
|---|---|
| Aliases | TBRS; DNMT3A2; M.HsaIIIA |
| Entrez GeneID | 1788 |
| Swissprot | Q9Y6K1 |
| clone | 4G5F11 |
| WB Predicted band size | 102kDa |
| Host/Isotype | Mouse IgG2a |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Purified recombinant fragment of human DNMT3A (AA: 46-180) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
|---|---|
| IHC | 1/200 - 1/1000 |
| FCM | 1/200 - 1/400 |
| ELISA | 1/10000 |
Product Image
- Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
- Flow cytometric analysis of Hela cells using DNMT3A mouse mAb (green) and negative control (red).
- Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using DNMT3A mouse mAb with DAB staining.
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#31016
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