Mouse Monoclonal Antibody to DNMT1

Description
DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene.

References
1.J Biol Chem. 2013 Jul 5;288(27):19673-84. 2.Int J Oncol. 2013 Jul;43(1):228-36.

Specification
Aliases	AIM; DNMT; MCMT; CXXC9; HSN1E; ADCADN
Entrez GeneID	1786
Swissprot	P26358
clone	2D10G8
WB Predicted band size	183.2kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant fragment of human DNMT1 (AA: 1317-1616) expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide

Application
IHC	1/200 - 1/1000
ELISA	1/10000