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Mouse Monoclonal Antibody to LEF1
-
货号:
30933 -
别名:
LEF-1; TCF10; TCF7L3; TCF1ALPHA -
产品上架时间:
2024-01-01 -
应用:
IHC -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
Q9UJU2 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180
Mouse Monoclonal Antibody to LEF1
Description |
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This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. |
References |
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1.Cancer Invest. 2014 Aug;32(7):368-74. 2.BMC Gastroenterol. 2012 May 28;12:53. |
Specification |
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Aliases | LEF-1; TCF10; TCF7L3; TCF1ALPHA |
Entrez GeneID | 51176 |
Swissprot | Q9UJU2 |
clone | 3G5F9 |
WB Predicted band size | 44.2kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human LEF1 (AA: 33-138) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
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IHC | 1/200 - 1/1000 |
ELISA | 1/10000 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#30933
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