Mouse Monoclonal Antibody to mTOR

Description
The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene.

References
1.Br J Cancer. 2015 Mar 17;112(6):1042-51. 2.Clin Cancer Res. 2014 Nov 1;20(21):5412-22.

Specification
Aliases	FRAP; FRAP1; FRAP2; RAFT1; RAPT1
Entrez GeneID	2475
Swissprot	P42345
clone	8H5A5
WB Predicted band size	289kDa
Host/Isotype	Mouse IgG2a
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat,Rabbit
Immunogen	Purified recombinant fragment of human mTOR (AA: 2311-2529) expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide

Application
IHC	1/200 - 1/1000
ELISA	1/10000