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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Immunohistochemical analysis of paraffin-embedded human liver cancer tissues using SIRT7 mouse mAb with DAB staining.
Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissues using SIRT7 mouse mAb with DAB staining.

Mouse Monoclonal Antibody to SIRT7

  • 货号:

    30893
  • 别名:

    SIR2L7
  • 产品上架时间:

    2024-01-01
  • 应用:

    IHC
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q9NRC8
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to SIRT7

Description

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.

References

1.Clin Cancer Res. 2014 Jul 1;20(13):3434-45.
2.Mol Cell Proteomics. 2014 Jan;13(1):73-83.

Specification

Aliases SIR2L7
Entrez GeneID 51547
Swissprot Q9NRC8
clone 1E2G10
WB Predicted band size 44.9kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human SIRT7 (AA: 1-105) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

IHC 1/200 - 1/1000
ELISA 1/10000