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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);

Western blot analysis using EZR mouse mAb against MCF-7 (1), Hela (2), A431 (3), Hek293 (4), SK-N-SH (5), Jurkat (6), HepG2 (7), NIH/3T3 (8), and Cos7 (9) cell lysate.

Immunofluorescence analysis of A549 cells using EZR mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Flow cytometric analysis of MCF-7 cells using EZR mouse mAb (green) and negative control (red).

Flow cytometric analysis of Hela cells using EZR mouse mAb (green) and negative control (red).

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Mouse Monoclonal Antibody to EZR

货号：
30799
别名：
CVL; CVIL; VIL2; HEL-S-105
产品上架时间：
2024-01-01
应用：
WB,IF,FCM
反应种属：
Human,Mouse,Monkey
抗体类型：
Primary antibody
Swissprot：
P15311
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Mouse Monoclonal Antibody to EZR

Description
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.

Description

The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.

References
1.BMC Cancer. 2013 Nov 4;13:520. 2.Cell Oncol (Dordr). 2013 Dec;36(6):485-91.

Specification
Aliases	CVL; CVIL; VIL2; HEL-S-105
Entrez GeneID	7430
Swissprot	P15311
clone	6F1A9
WB Predicted band size	69.4kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Monkey
Immunogen	Purified recombinant fragment of human EZR (AA: 292-464) expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide