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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);

Western blot analysis using EZR mouse mAb against MCF-7 (1), Hela (2), A431 (3), Hek293 (4), SK-N-SH (5), Jurkat (6), HepG2 (7), NIH/3T3 (8), and Cos7 (9) cell lysate.

Immunofluorescence analysis of A549 cells using EZR mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Flow cytometric analysis of MCF-7 cells using EZR mouse mAb (green) and negative control (red).

Flow cytometric analysis of Hela cells using EZR mouse mAb (green) and negative control (red).

Mouse Monoclonal Antibody to EZR

货号：
30799
别名：
CVL; CVIL; VIL2; HEL-S-105
产品上架时间：
2024-01-01
应用：
WB,IF,FCM
反应种属：
Human,Mouse,Monkey
抗体类型：
Primary antibody
Swissprot：
P15311
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Mouse Monoclonal Antibody to EZR

Description
The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.

Description

The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.

References
1.BMC Cancer. 2013 Nov 4;13:520. 2.Cell Oncol (Dordr). 2013 Dec;36(6):485-91.

Specification
Aliases	CVL; CVIL; VIL2; HEL-S-105
Entrez GeneID	7430
Swissprot	P15311
clone	6F1A9
WB Predicted band size	69.4kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Monkey
Immunogen	Purified recombinant fragment of human EZR (AA: 292-464) expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide