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Mouse Monoclonal Antibody to MAP3K7
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货号:
30765 -
别名:
TAK1; MEKK7; TGF1a -
产品上架时间:
2024-01-01 -
应用:
-
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
O43318 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180
Mouse Monoclonal Antibody to MAP3K7
Description |
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The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. |
References |
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Asian Pac J Cancer Prev. 2013;14(1):315-20. Blood. 2012 Jul 12;120(2):347-55. |
Specification |
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Aliases | TAK1; MEKK7; TGF1a |
Entrez GeneID | 6885 |
Swissprot | O43318 |
clone | 3E8H4 |
WB Predicted band size | 67.2kDa |
Host/Isotype | Mouse IgG2a |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human MAP3K7 (AA: 471-579) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer. |
Application |
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ELISA | 1/10000 |
Product Image
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#30765
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