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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);

Immunofluorescence analysis of Hela cells using NOX4 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)

Flow cytometric analysis of Hela cells using NOX4 mouse mAb (green) and negative control (red).

Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using NOX4 mouse mAb with DAB staining.

Immunohistochemical analysis of paraffin-embedded human bladder cancer tissues using NOX4 mouse mAb with DAB staining.

Mouse Monoclonal Antibody to NOX4

货号：
30754
别名：
KOX; KOX-1; RENOX
产品上架时间：
2024-01-01
应用：
IHC,IF,FCM
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q9NPH5
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Mouse Monoclonal Antibody to NOX4

Description
This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.

Description

This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.

References
Stem Cells Dev. 2012 Aug 10;21(12):2212-21. Cancer Biol Ther. 2010 Aug 1;10(3):223-31.

Specification
Aliases	KOX; KOX-1; RENOX
Entrez GeneID	50507
Swissprot	Q9NPH5
clone	3H2G11
WB Predicted band size	67kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant fragment of human NOX4 (AA: 210-310) expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide