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Western blot analysis of lysates from human liver tissue and mouse NIH/3T3 cell line(from left to right), using (Mouse) Wdr5 Antibody(Cat. #P32849). P32849 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.

Rabbit Polyclonal Antibody to (Mouse) Wdr5

货号：
P32849
别名：
WD repeat-containing protein 5, BMP2-induced 3-kb gene protein, WD repeat-containing protein BIG-3, Wdr5, Big, Big3
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human, Mouse, Rat
抗体类型：
Primary antibody
Swissprot：
P61965
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to (Mouse) Wdr5

Description
Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation (By similarity).

Description

Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation (By similarity).

Specification
Aliases	WD repeat-containing protein 5, BMP2-induced 3-kb gene protein, WD repeat-containing protein BIG-3, Wdr5, Big, Big3
Entrez GeneID	140858
Swissprot	P61965
WB Predicted band size	36.6kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	This Mouse Wdr5 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from the region of mouse Wdr5.