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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Western blot analysis using XRCC6 mouse mAb against PC-2 (1), A549 (2), A431 (3), HepG2 (4), K562 (5) cell lysate.
Immunofluorescence analysis of MCF-7 cells using XRCC6 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
Flow cytometric analysis of A431 cells using XRCC6 mouse mAb (green) and negative control (red).

Mouse Monoclonal Antibody to XRCC6

  • 货号:

    30698
  • 别名:

    ML8; KU70; TLAA; CTC75; CTCBF; G22P1
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IF,FCM
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P12956
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to XRCC6

Description

The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.

References

1. Clin Cancer Res. 2013 Mar 15;19(6):1547-56.
2. Mol Carcinog. 2012 Oct;51 Suppl 1:E183-90.

Specification

Aliases ML8; KU70; TLAA; CTC75; CTCBF; G22P1
Entrez GeneID 2547
Swissprot P12956
clone 7A9E7
WB Predicted band size 69.8kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human XRCC6 (AA: 6-214) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500 - 1/2000
IF 1/200 - 1/1000
FCM 1/200 - 1/400
ELISA 1/10000