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Mouse Monoclonal Antibody to XRCC6
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货号:
30698 -
别名:
ML8; KU70; TLAA; CTC75; CTCBF; G22P1 -
产品上架时间:
2024-01-01 -
应用:
WB,IF,FCM -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
P12956 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180
Mouse Monoclonal Antibody to XRCC6
Description |
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The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. |
References |
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1. Clin Cancer Res. 2013 Mar 15;19(6):1547-56. 2. Mol Carcinog. 2012 Oct;51 Suppl 1:E183-90. |
Specification |
|
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Aliases | ML8; KU70; TLAA; CTC75; CTCBF; G22P1 |
Entrez GeneID | 2547 |
Swissprot | P12956 |
clone | 7A9E7 |
WB Predicted band size | 69.8kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human XRCC6 (AA: 6-214) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide. |
Application |
|
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WB | 1/500 - 1/2000 |
IF | 1/200 - 1/1000 |
FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
- Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
- Western blot analysis using XRCC6 mouse mAb against PC-2 (1), A549 (2), A431 (3), HepG2 (4), K562 (5) cell lysate.
- Immunofluorescence analysis of MCF-7 cells using XRCC6 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin. Secondary antibody from Fisher (Cat#: 35503)
- Flow cytometric analysis of A431 cells using XRCC6 mouse mAb (green) and negative control (red).
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#30698
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