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TSC1 Antibody (Center T417) (Cat. #P32463) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the TSC1 antibody detected the TSC1 protein (arrow).

Rabbit Polyclonal Antibody to TSC1 (Center T417)

货号：
P32463
别名：
Hamartin, Tuberous sclerosis 1 protein, TSC1, KIAA0243, TSC
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q92574
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to TSC1 (Center T417)

Description
In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling.

Specification
Aliases	Hamartin, Tuberous sclerosis 1 protein, TSC1, KIAA0243, TSC
Entrez GeneID	7248
Swissprot	Q92574
WB Predicted band size	129.8kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This TSC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 395-424 amino acids from the Central region of human TSC1.
Formulation	Purified antibody in PBS with 0.05% sodium azide.