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Dot blot analysis of rat TSC1 Antibody (Phospho S312) Phospho-specific Pab (Cat. #P32407) on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.

Rabbit Polyclonal Antibody to Phospho-rat TSC1(S312)

  • 货号:

    P32407
  • 别名:

    Hamartin, Tuberous sclerosis 1 protein homolog, Tsc1
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB
  • 反应种属:

    Rat
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q9Z136
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Rabbit Polyclonal Antibody to Phospho-rat TSC1(S312)

Description

In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).

Specification

Aliases Hamartin, Tuberous sclerosis 1 protein homolog, Tsc1
Entrez GeneID 60445
Swissprot Q9Z136
WB Predicted band size 129.0kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Rat
Immunogen This rat TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S312 of rat TSC1.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB DB: 1/500

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#P32407