Rabbit Polyclonal Antibody to Phospho-mouse TSC1(S594)

Description
In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).

Specification
Aliases	Hamartin, Tuberous sclerosis 1 protein homolog, Tsc1, Kiaa0243
Entrez GeneID	64930
Swissprot	Q9EP53
WB Predicted band size	128.7kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Mouse
Immunogen	This mouse TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S594 of mouse TSC1.
Formulation	Purified antibody in PBS with 0.05% sodium azide.

Application
WB	DB: 1/500