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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Western blot analysis using EIF2AK2 mouse mAb against A431 (1), THP-1 (2), MCF-7 (3), PC-12 (4) cell lysate.
Flow cytometric analysis of A431 cells using EIF2AK2 mouse mAb (green) and negative control (red).
Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using EIF2AK2 mouse mAb with DAB staining.
Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using EIF2AK2 mouse mAb with DAB staining.
Immunohistochemical analysis of paraffin-embedded Rabbit kidney using EIF2AK2 mouse mAb with DAB staining.
Immunohistochemical analysis of paraffin-embedded Rabbit rectum using EIF2AK2 mouse mAb with DAB staining.

Mouse Monoclonal Antibody to EIF2AK2

  • 货号:

    30680
  • 别名:

    PKR; PRKR; EIF2AK1
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC,FCM
  • 反应种属:

    Human,Mouse,Rat,Rabbit
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P19525
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to EIF2AK2

Description

The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.

References

1. J Alzheimers Dis. 2010;21(4):1217-31.
2. Mol Cells. 2011 Aug;32(2):167-72.

Specification

Aliases PKR; PRKR; EIF2AK1
Entrez GeneID 5610
Swissprot P19525
clone 6H3A10
WB Predicted band size 62kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat,Rabbit
Immunogen Purified recombinant fragment of human EIF2AK2 (AA: 329-551) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/500 - 1/2000
IHC 1/100 - 1/500
FCM 1/200 - 1/400
ELISA 1/10000