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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Immunofluorescence analysis of HepG2 cells using RPTOR mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Secondary antibody from Fisher (Cat#: 35503)
Immunohistochemical analysis of paraffin-embedded human muscle tissues using RPTOR mouse mAb with DAB staining.

Mouse Monoclonal Antibody to RPTOR

  • 货号:

    30652
  • 别名:

    KOG1; Mip1
  • 产品上架时间:

    2024-01-01
  • 应用:

    IHC,ICC
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q8N122
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to RPTOR

Description

This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene.

References

1. PLoS Genet. 2010 Oct 28;6(10):e1001178.
2. Cell Cycle. 2011 Sep 15;10(18):3140-52.

Specification

Aliases KOG1; Mip1
Entrez GeneID 57521
Swissprot Q8N122
clone 5A3A4
WB Predicted band size 149kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human RPTOR (AA: 874-1009) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

IHC 1/200 - 1/1000
ICC 1/200 - 1/1000
ELISA 1/10000