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Mouse Tbk1 Antibody (N-term) (Cat. #P31778) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the Tbk1 antibody detected the Tbk1 protein (arrow).

Rabbit Polyclonal Antibody to Mouse Tbk1 (N-term)

货号：
P31778
别名：
Serine/threonine-protein kinase TBK1, T2K, TANK-binding kinase 1, Tbk1
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Mouse
抗体类型：
Primary antibody
Swissprot：
Q9WUN2
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to Mouse Tbk1 (N-term)

Description
Serine/threonine protein involved in the signaling cascade converging to the activation of the transcription factor NF-kappa-B. May function as an IKK kinase, playing an essential role in the transcription of a subset of a TNF-alpha-induced genes. Also mediates production of RANTES/CCL5 and interferon-beta/IFNB1. Has a pivotal role in the innate immune response. Phosphorylates and activates IRF3 and IRF7 and allows their nuclear localization. This leads to production of alpha/beta interferons and the development of a cellular antiviral state. It also seems to be a central factor in the induction of the antiviral interferon response.

Description

Serine/threonine protein involved in the signaling cascade converging to the activation of the transcription factor NF-kappa-B. May function as an IKK kinase, playing an essential role in the transcription of a subset of a TNF-alpha-induced genes. Also mediates production of RANTES/CCL5 and interferon-beta/IFNB1. Has a pivotal role in the innate immune response. Phosphorylates and activates IRF3 and IRF7 and allows their nuclear localization. This leads to production of alpha/beta interferons and the development of a cellular antiviral state. It also seems to be a central factor in the induction of the antiviral interferon response.

Specification
Aliases	Serine/threonine-protein kinase TBK1, T2K, TANK-binding kinase 1, Tbk1
Entrez GeneID	56480
Swissprot	Q9WUN2
WB Predicted band size	83.4kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Mouse
Immunogen	This Mouse Tbk1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-35 amino acids from the N-terminal region of mouse Tbk1.
Formulation	Purified antibody in PBS with 0.05% sodium azide.