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IMPDH1 Antibody (C-term) (Cat. #P31308) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the IMPDH1 antibody detected the IMPDH1 protein (arrow).
Confocal immunofluorescent analysis of IMPDH1 Antibody (C-term) (Cat#P31308) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
IMPDH1 Antibody (C-term) (P31308)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of IMPDH1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Rabbit Polyclonal Antibody to IMPDH1

  • 货号:

    P31308
  • 别名:

    Inosine-5'-monophosphate dehydrogenase 1 {ECO:0000255|HAMAP-Rule:MF_03156}, IMP dehydrogenase 1 {ECO:0000255|HAMAP-Rule:MF_03156}, IMPD 1 {ECO:0000255|HAMAP-Rule:MF_03156}, IMPDH 1 {ECO:0000255|HAMAP-Rule:MF_03156}, 111205 {ECO:0000255|HAMAP-Rule:MF_03156}, IMPDH-I, IMPDH1 {ECO:0000255|HAMAP-Rule:MF_03156}, IMPD1
  • 产品上架时间:

    2024-01-01
  • 应用:

    WB,IHC,IF
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    P20839
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥1980

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Rabbit Polyclonal Antibody to IMPDH1

Description

The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.

Specification

Aliases Inosine-5'-monophosphate dehydrogenase 1 {ECO:0000255|HAMAP-Rule:MF_03156}, IMP dehydrogenase 1 {ECO:0000255|HAMAP-Rule:MF_03156}, IMPD 1 {ECO:0000255|HAMAP-Rule:MF_03156}, IMPDH 1 {ECO:0000255|HAMAP-Rule:MF_03156}, 111205 {ECO:0000255|HAMAP-Rule:MF_03156}, IMPDH-I, IMPDH1 {ECO:0000255|HAMAP-Rule:MF_03156}, IMPD1
Entrez GeneID 3614
Swissprot P20839
WB Predicted band size 55.4kDa
Host/Isotype Rabbit IgG
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen This IMPDH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 487-514 amino acids from the C-terminal region of human IMPDH1.
Formulation Purified antibody in PBS with 0.05% sodium azide.

Application

WB 1/1000
IHC 1/100-1/500
IF 1/10-1/50