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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);

Immunofluorescence analysis of Hela cells using MLXIPL mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.

Mouse Monoclonal Antibody to MLXIPL

货号：
30575
别名：
MIO; CHREBP; MONDOB; WBSCR14; WS-bHLH; bHLHd14
产品上架时间：
2024-01-01
应用：
IF
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q9NP71
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥2180

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Mouse Monoclonal Antibody to MLXIPL

Description
This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.

Description

This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23.

References
1. Diabetes. 2012 Mar;61(3):574-85. 2. Biochim Biophys Acta. 2011 Dec;1811(12):1194-200.

Specification
Aliases	MIO; CHREBP; MONDOB; WBSCR14; WS-bHLH; bHLHd14
Entrez GeneID	51085
Swissprot	Q9NP71
clone	5D12D1
WB Predicted band size	93.1kDa
Host/Isotype	Mouse IgG1
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Purified recombinant fragment of human MLXIPL (AA: 18-143) expressed in E. Coli.
Formulation	Purified antibody in PBS with 0.05% sodium azide.