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PITRM1 Antibody (Center) (Cat. #P31078) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the PITRM1 antibody detected the PITRM1 protein (arrow).

Rabbit Polyclonal Antibody to PITRM1

货号：
P31078
别名：
Presequence protease, mitochondrial, hPreP, 3424-, Pitrilysin metalloproteinase 1, Metalloprotease 1, hMP1, PITRM1, KIAA1104, MP1
产品上架时间：
2024-01-01
应用：
WB
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q5JRX3
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to PITRM1

Description
ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.

Description

ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides. Specific for peptides in the range of 10 to 65 residues. Able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer disease. Shows a preference for cleavage after small polar residues and before basic residues, but without any positional preference.

Specification
Aliases	Presequence protease, mitochondrial, hPreP, 3424-, Pitrilysin metalloproteinase 1, Metalloprotease 1, hMP1, PITRM1, KIAA1104, MP1
Entrez GeneID	10531
Swissprot	Q5JRX3
WB Predicted band size	117.4kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This PITRM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 490-518 amino acids from the Central region of human PITRM1.
Formulation	Purified antibody in PBS with 0.05% sodium azide.