提醒成功
搜索
Mouse Monoclonal Antibody to EGFR
-
货号:
30551 -
别名:
ERBB; HER1; mENA; ERBB1; PIG61 -
产品上架时间:
2024-01-01 -
应用:
WB,FCM -
反应种属:
Human,Mouse,Rat -
抗体类型:
Primary antibody -
Swissprot:
P00533 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180
Mouse Monoclonal Antibody to EGFR
Description |
---|
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. |
References |
---|
1. J Immunol. 2012 Dec 1;189(11):5230-9. 2. J Biol Chem. 2012 Oct 12;287(42):35201-11. |
Specification |
|
---|---|
Aliases | ERBB; HER1; mENA; ERBB1; PIG61 |
Entrez GeneID | 1956 |
Swissprot | P00533 |
clone | 5E10D3 |
WB Predicted band size | 175kDa |
Host/Isotype | Mouse IgG2b |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse,Rat |
Immunogen | Purified recombinant fragment of human EGFR (AA: 693-893) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
---|---|
WB | 1/500 - 1/2000 |
FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
- Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
- Western blot analysis using EGFR mouse mAb against A431 (1) AND Hela (2) cell lysate.
- Western blot analysis using EGFR mouse mAb against C2C12(1),81505(2) cell lysate.
- Flow cytometric analysis of A431 cells using EGFR mouse mAb (green) and negative control (red).
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#30551
相关产品