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Mouse Monoclonal Antibody to CD74
-
货号:
30532 -
别名:
II; DHLAG; HLADG; Ia-GAMMA -
产品上架时间:
2024-01-01 -
应用:
WB,IF,FCM -
反应种属:
Human -
抗体类型:
Primary antibody -
Swissprot:
P04233 -
规格:
-
数量:
-+ -
说明书:
目录价¥2180
Mouse Monoclonal Antibody to CD74
Description |
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The protein encoded by this gene associates with class II major histocompatibility complex (MHC) and is an important chaperone that regulates antigen presentation for immune response. It also serves as cell surface receptor for the cytokine macrophage migration inhibitory factor (MIF) which, when bound to the encoded protein, initiates survival pathways and cell proliferation. This protein also interacts with amyloid precursor protein (APP) and suppresses the production of amyloid beta (Abeta). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. |
References |
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1. Tumour Biol. 2012 Dec;33(6):2273-7. 2. World J Gastroenterol. 2012 May 14;18(18):2253-61. |
Specification |
|
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Aliases | II; DHLAG; HLADG; Ia-GAMMA |
Entrez GeneID | 972 |
Swissprot | P04233 |
clone | 2D1B3 |
WB Predicted band size | 33.5kDa |
Host/Isotype | Mouse IgG1 |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Purified recombinant fragment of human CD74 (AA: 1-106) expressed in E. Coli. |
Formulation | Purified antibody in PBS with 0.05% sodium azide |
Application |
|
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WB | 1/500 - 1/2000 |
IF | 1/200 - 1/1000 |
FCM | 1/200 - 1/400 |
ELISA | 1/10000 |
Product Image
- Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
- Western blot analysis using CD74 mouse mAb against Raji cell lysate.
- Immunofluorescence analysis of Hela cells using CD74 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye.
- Flow cytometric analysis of Jurkat cells using CD74 mouse mAb (green) and negative control (red).
For Reseach Only
Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
#30532
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