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Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng);
Immunofluorescence analysis of HepG2 cells using NRCAM mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
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Mouse Monoclonal Antibody to NRCAM

  • 货号:

    30490
  • 别名:

    NRCAM
  • 产品上架时间:

    2024-01-01
  • 应用:

    IF
  • 反应种属:

    Human
  • 抗体类型:

    Primary antibody
  • Swissprot:

    Q92823
  • 规格:

  • 数量:

    -
    +
  • 说明书:

    目录价¥2180

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Mouse Monoclonal Antibody to NRCAM

Description

Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily. This gene encodes a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains. This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth. This gene is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration. Allelic variants of this gene have been associated with autism and addiction vulnerability. Alternative splicing results in multiple transcript variants encoding different isoforms.

References

1. Psychiatry Clin Neurosci. 2009 Feb;63(1):123-4.
2. Int J Neuropsychopharmacol. 2009 Feb;12(1):1-10.

Specification

Aliases NRCAM
Entrez GeneID 4897
Swissprot Q92823
clone 7D8C5
WB Predicted band size 144kDa
Host/Isotype Mouse IgG1
Antibody Type Primary antibody
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Purified recombinant fragment of human NRCAM (AA: 1192-1255) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide

Application

IF 1/50
ELISA 1/10000

For Reseach Only

Application Key:WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation

#30490