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Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human brain malignant glioma tissue, Human laryngocarcinoma tissue, Primary antibody: P11051(YWHAE Antibody) at dilution 1/2200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds

The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P11051(YWHAE Antibody) at dilution 1/100. (Original magnification: ×200)

The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P11051(YWHAE Antibody) at dilution 1/100. (Original magnification: ×200)

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Rabbit Polyclonal Antibody to YWHAE

货号：
P11051
别名：
MDS, MDCR, KCIP-1, 14-3-3E
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human, Mouse, Rat
抗体类型：
Primary antibody
Swissprot：
P62258
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to YWHAE

Description
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene.

Description

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene.

Specification
Aliases	MDS, MDCR, KCIP-1, 14-3-3E
Swissprot	P62258
WB Predicted band size	29 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide of human YWHAE
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.