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Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: K562 cells, Primary antibody: P10743(CDC6 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes

The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P10743(CDC6 Antibody) at dilution 1/25. (Original magnification: ×200)

The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P10743(CDC6 Antibody) at dilution 1/25. (Original magnification: ×200)

HOT

Rabbit Polyclonal Antibody to CDC6

货号：
P10743
别名：
CDC18L; HsCDC6; MGORS5; HsCDC18
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q99741
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to CDC6

Description
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.

Description

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.

Specification
Aliases	CDC18L; HsCDC6; MGORS5; HsCDC18
Swissprot	Q99741
WB Predicted band size	63 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthetic peptide of human CDC6
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.