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Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: PC-3 cell lysate, Primary antibody: P10576(LRWD1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 3 minutes

The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P10576(LRWD1 Antibody) at dilution 1/80. (Original magnification: ×200)

The image is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using P10576(LRWD1 Antibody) at dilution 1/80. (Original magnification: ×200)

Rabbit Polyclonal Antibody to LRWD1

货号：
P10576
别名：
ORCA; CENP-33
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human
抗体类型：
Primary antibody
Swissprot：
Q9UFC0
规格：

100μl
50μl
20μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to LRWD1

Description
The protein encoded by this gene interacts with components of the origin recognition complex (ORC) and regulates the formation of the prereplicative complex. The encoded protein stabilizes the ORC and therefore aids in DNA replication. This protein is required for the G1/S phase transition of the cell cycle. In addition, the encoded protein binds to trimethylated histone H3 in heterochromatin and recruits the ORC and lysine methyltransferases, which help maintain the repressive heterochromatic state. Two transcript variants encoding different isoforms have been found for this gene.

Description

The protein encoded by this gene interacts with components of the origin recognition complex (ORC) and regulates the formation of the prereplicative complex. The encoded protein stabilizes the ORC and therefore aids in DNA replication. This protein is required for the G1/S phase transition of the cell cycle. In addition, the encoded protein binds to trimethylated histone H3 in heterochromatin and recruits the ORC and lysine methyltransferases, which help maintain the repressive heterochromatic state. Two transcript variants encoding different isoforms have been found for this gene.

Specification
Aliases	ORCA; CENP-33
Swissprot	Q9UFC0
WB Predicted band size	71 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Fusion protein of human LRWD1
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.