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The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P10328(PPM1M Antibody) at dilution 1/100. (Original magnification: ×200)

The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P10328(PPM1M Antibody) at dilution 1/100. (Original magnification: ×200)

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Rabbit Polyclonal Antibody to PPM1M

货号：
P10328
别名：
PP2CE; PP2Ceta; PP2C-eta
产品上架时间：
2024-01-01
应用：
IHC
反应种属：
Human, Mouse
抗体类型：
Primary antibody
Swissprot：
Q96MI6
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to PPM1M

Description
PPM1M is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase was identified as an interacting protein of Rho guanine nucleotide exchange factors (PIX). PIX proteins are regulators of p21/Cdc42/Rac1-activated kinase 1 (PAK1), a protein kinase mediating biological effects downstream of Rho GTPases. This phosphatase has been shown to block the effects of PAK, and thus inhibit actin stress fiber breakdown and morphological changes driven by cell division cycle 42 (CDC42).

Description

PPM1M is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase was identified as an interacting protein of Rho guanine nucleotide exchange factors (PIX). PIX proteins are regulators of p21/Cdc42/Rac1-activated kinase 1 (PAK1), a protein kinase mediating biological effects downstream of Rho GTPases. This phosphatase has been shown to block the effects of PAK, and thus inhibit actin stress fiber breakdown and morphological changes driven by cell division cycle 42 (CDC42).

Specification
Aliases	PP2CE; PP2Ceta; PP2C-eta
Swissprot	Q96MI6
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Fusion protein of human PPM1M
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.