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Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-6: NIH/3T3 cell, Mouse Pancreas tissue, Rat lung tissue, Mouse liver tissue, Hela, Raji cell lysates, Primary antibody: P10314(TMED10 Antibody) at dilution 1/900, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 30 seconds

The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P10314(TMED10 Antibody) at dilution 1/65. (Original magnification: ×200)

The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P10314(TMED10 Antibody) at dilution 1/65. (Original magnification: ×200)

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Rabbit Polyclonal Antibody to TMED10

货号：
P10314
别名：
p23; TMP21; p24d1; S31I125; Tmp-21-I; S31III125; P24(DELTA)
产品上架时间：
2024-01-01
应用：
WB,IHC
反应种属：
Human, Mouse, Rat
抗体类型：
Primary antibody
Swissprot：
P49755
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to TMED10

Description
This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.

Description

This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.

Specification
Aliases	p23; TMP21; p24d1; S31I125; Tmp-21-I; S31III125; P24(DELTA)
Swissprot	P49755
WB Predicted band size	25 kDa
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Fusion protein of human TMED10
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.