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The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P10157(IFT57 Antibody) at dilution 1/85. (Original magnification: ×200)
Rabbit Polyclonal Antibody to IFT57
-
货号：
P10157 -
别名：
HIPPI; MHS4R2; ESRRBL1 -
应用：
IHC -
反应种属：
Human, Mouse -
抗体类型：
Primary antibody -
Swissprot：
Q9NWB7 -
规格：
-
数量：
-+ -
说明书：
目录价¥2180
Rabbit Polyclonal Antibody to IFT57
Description |
|---|
Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear. |
Specification |
|
|---|---|
| Aliases | HIPPI; MHS4R2; ESRRBL1 |
| Swissprot | Q9NWB7 |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human IFT57 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
|---|---|
| IHC | 1/50-1/300 |
| ELISA | 1/5000-1/10000 |
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
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