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The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P10002(MPZL1 Antibody) at dilution 1/25. (Original magnification: ×200)

The image is immunohistochemistry of paraffin-embedded Human brain tissue using P10002(MPZL1 Antibody) at dilution 1/25. (Original magnification: ×200)

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Rabbit Polyclonal Antibody to MPZL1

货号：
P10002
别名：
PZR; PZRa; PZRb; PZR1b; MPZL1b
产品上架时间：
2024-01-01
应用：
IHC
反应种属：
Human, Mouse, Rat
抗体类型：
Primary antibody
Swissprot：
O95297
规格：

100μl
50μl
数量：

-

+
说明书：

目录价¥1980

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Rabbit Polyclonal Antibody to MPZL1

Description
Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.

Description

Cell surface receptor, which is involved in signal transduction processes. Recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. Is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases. Isoform 3 seems to have a dominant negative role; it blocks tyrosine phosphorylation of MPZL1 induced by ConA. Isoform 1, but not isoform 2 and isoform 3, may be involved in regulation of integrin-mediated cell motility.

Specification
Aliases	PZR; PZRa; PZRb; PZR1b; MPZL1b
Swissprot	O95297
Host/Isotype	Rabbit IgG
Antibody Type	Primary antibody
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Fusion protein of human MPZL1
Formulation	Purified antibody in PBS with 0.05% sodium azide and 50% glycerol.