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The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P09574(CYFIP1 Antibody) at dilution 1/30. (Original magnification: ×200)
Rabbit Polyclonal Antibody to CYFIP1
-
货号：
P09574 -
别名：
SHYC; SRA1; SRA-1; P140SRA-1 -
应用：
IHC -
反应种属：
Human, Mouse -
抗体类型：
Primary antibody -
Swissprot：
Q7L576 -
规格：
-
数量：
-+ -
说明书：
目录价¥1980
Rabbit Polyclonal Antibody to CYFIP1
Description |
|---|
Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Regulates formation of membrane ruffles and lamellipodia. Plays a role in axon outgrowth. Binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. May act as an invasion suppressor in cancers. |
Specification |
|
|---|---|
| Aliases | SHYC; SRA1; SRA-1; P140SRA-1 |
| Swissprot | Q7L576 |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Fusion protein of human CYFIP1 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
Application |
|
|---|---|
| IHC | 1/25-1/100 |
| ELISA | 1/500-1/1000 |
For Reseach Only
Application Key：WB - Western Blot | IHC - Immunohistochemistry | ICC - Immunocytochemistry | FCM - Flow Cytometry | ELISA - Enzyme-linked Immunosorbent Assay | IP - Immunoprecipitation
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